2026-1학기 전산전자공학대학원 여섯 번째 세미나 강의를 소개합니다. We are pleased to announce the commencement of the 2026 Spring Semester Seminar Series for the Graduate School of Computer Science and Electrical Engineering. This weekly forum serves as a cornerstone for academic exchange, bringing together students, faculty, and industry experts to explore the frontiers of modern technology.
강사(Speaker): 배장한 박사 (한국한의학연구원)
제목(Title): Altered temporal dynamics of prefrontal ERP responses reflecting neural adaptation in patients with amnestic mild cognitive impairment
일시(Date): 5월 15일 금요일, 오후 4시 | May 15, Friday
장소(Venue): 뉴턴홀 310호
발표언어(Language): 한국어
강의초록(Abstract): With the rapid aging of the population, mild cognitive impairment (MCI), particularly amnestic MCI (aMCI), has emerged as a major public health concern due to its high risk of progression to Alzheimer’s disease (AD). This seminar introduces a recent study that investigates the neural mechanisms of early cognitive decline by focusing on the temporal dynamics of prefrontal event-related potentials (ERPs), addressing the limitations of conventional grand-averaged approaches. Prefrontal ERPs were recorded with a portable EEG system during an auditory oddball task. The study quantified trial-by-trial changes in the P200 component, employing temporal segmentation, repeated-measures ANOVA, and individual slope-based regression analyses to characterize neural adaptation across groups. The findings demonstrate that the aMCI group exhibits accelerated attenuation of P200 responses over repeated trials, suggesting altered attentional allocation and reduced neural efficiency. In contrast, cognitively normal participants show relatively stable response patterns. Importantly, these temporal dynamic measures appear more sensitive to group differences than conventional static averages. This seminar will provide a structured overview of ERP temporal dynamics and associated analytical frameworks, and discuss the potential of slope-based indices as noninvasive biomarkers for early detection of AD risk. The session aims to highlight the importance of time-resolved neural signal analysis in both cognitive neuroscience research and clinical applications.
본 세미나는 오프라인으로 진행됩니다. 학부생, 대학원생, 교직원 누구나 참여 가능하니 많은 관심과 참여 바랍니다. This seminar will be conducted offline. We welcome all undergraduate students, graduate students, faculty, and staff to join us. We look forward to your interest and active participation.
2026-1학기 전산전자공학대학원 여섯 번째 세미나 강의를 소개합니다. We are pleased to announce the commencement of the 2026 Spring Semester Seminar Series for the Graduate School of Computer Science and Electrical Engineering. This weekly forum serves as a cornerstone for academic exchange, bringing together students, faculty, and industry experts to explore the frontiers of modern technology.
This seminar introduces a recent study that investigates the neural mechanisms of early cognitive decline by
focusing on the temporal dynamics of prefrontal event-related potentials (ERPs), addressing the limitations of
conventional grand-averaged approaches.
Prefrontal ERPs were recorded with a portable EEG system during an auditory oddball task. The study
quantified trial-by-trial changes in the P200 component, employing temporal segmentation, repeated-measures
ANOVA, and individual slope-based regression analyses to characterize neural adaptation across groups.
The findings demonstrate that the aMCI group exhibits accelerated attenuation of P200 responses over repeated
trials, suggesting altered attentional allocation and reduced neural efficiency. In contrast, cognitively normal
participants show relatively stable response patterns. Importantly, these temporal dynamic measures appear
more sensitive to group differences than conventional static averages.
This seminar will provide a structured overview of ERP temporal dynamics and associated analytical
frameworks, and discuss the potential of slope-based indices as noninvasive biomarkers for early detection of
AD risk. The session aims to highlight the importance of time-resolved neural signal analysis in both cognitive
neuroscience research and clinical applications.
문의 (Inquiry): 054-260-3150(BK21 AI사업단)
본 세미나는 오프라인으로 진행됩니다. 학부생, 대학원생, 교직원 누구나 참여 가능하니 많은 관심과 참여 바랍니다. This seminar will be conducted offline. We welcome all undergraduate students, graduate students, faculty, and staff to join us. We look forward to your interest and active participation.